7-hydroxymitragynin

7-hydroxymitragynine and its effect on the human body

7-Hydroxymitragynine (7-HMG) is the active ingredient of the plant Mitragyna speciosa, also known as Kratom, which is naturally found in Southeast Asia. 7-HMG is usually used as an analgesic and to treat anxiety disorders for its potential effects on the human body. This article focuses on the subject of 7-HMG and its effects on the human body, including its chemical composition, disposition, and what it affects.


7-Hydroxymitragynine is an alkaloid of the mitragynine group and is the most impressive and powerful analgesic in the Kratom plant. Its effects are usually combined with other Mitragyna speciosa alkaloids such as Mitragynine or Paynanthein. Once inside the human body, it activates the central nervous system, which can lead to reduction of pain and inflammation.

7-HMG also has hypnotic properties and helps reduce anxiety states, depression and sleep problems. It also affects the production of serotonin in the human body. Serotonin is a neurochemical that regulates mood and emotions. An increased level of serotonin can therefore have a positive effect on the human psyche.

The chemical formula of 7-hydroxymitragynine is C23H30N2O7. Its molecular weight is 414.50 g/mol. It has a high affinity for the κ-opioid receptor and a high potency for activating the μ-opioid receptor. 7-HMG also affects calcium channels in the heart, which can cause cardiac arrhythmias and worsening of heart conditions.

The use of Kratom and therefore 7-hydroxymitragynine is controversial. Kratom is banned in some countries and can be dangerous if taken in excess. When used in excess, it can cause addiction and other side effects such as vomiting, diarrhea, low blood pressure or convulsions.


7-Hydroxymitragynine is the active component of the Kratom plant and has potential for use as an analgesic and for the treatment of anxiety disorders. When used correctly and following the recommended dosage, it can be a very useful substance for human health. However, we must be aware of possible side effects and follow the recommended doses. It is important to consult a doctor when using Kratom and to stick to the recommended dosage to avoid any side effects and risks to our health.
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